UNRAVELLING ANTIGENIC CROSS-REACTIONS TOWARD THE WORLD OF CORONAVIRUSES: EXTENT OF THE STABILITY OF SHARED EPITOPES AND SARS-COV-2 ANTI-SPIKE CROSS-NEUTRALIZING ANTIBODIES

The human immune repertoire retains the molecular memory of a very great diversity of target antigens (epitopes) and can recall this upon a second encounter with epitopes against which it has previously been primed.Although genetically diverse, proteins of coronaviruses exhibit sufficient conservation to lead to antigenic cross-reactions.In this re

Microorganism culture is highly complex due to the different metabolic pathways, which are very complex.A metabolic phenomenon called overflow is a challenge to overcome in automatic control tasks of microorganism cultures.In this study, a nonlinear algorithm by sliding modes (sliding mode nonlinear control, SMNC) is proposed for the robust regulat

Health-related quality of life (HRQOL) measures are used to assess the multifaceted impact of disease, and determine the utility and associated disability.In addition, the impact of medical interventions must be assessed by psychometrically robust HRQOL measures Rattle Blanket based on a comprehensive and dynamic model.To develop such a model, the